Non-Personalized, Active Immunotherapy

1. Oncolipin-IT Colorectal Cancer (Multilamellar coalescent vesicle, MLCV):

  • Description: Synthetic multilamellar liposomes with recombinant human IL-2, produced on Oncolipin platform technology

  • Stage: Pre-clinical animal model research

  • Clinical indication: For “in-situ” vaccination (Neville et al, Cytokine, 2001, 16: 239) of patients with operable / inoperable bulky Colorectal cancer liver metastasis.

  • PI: Dr. Ajay Maker, M.D., University of Illinois, Chicago.

2. Oncoquest™-PC:

  • Description: Aggregon® with a recombinant human IL-2 and off-the-shelf common tumor antigen(s) found in Prostate cancer 

  • Stage: Research phase

  • Clinical indication: Patients with early stage prostate cancer;

  • PI: To be determined (TBD)