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Non-Personalized, Active Immunotherapy
1. Oncolipin-IT Colorectal Cancer (Multilamellar coalescent vesicle, MLCV):
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Description: Synthetic multilamellar liposomes with recombinant human IL-2, produced on Oncolipin platform technology
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Stage: Pre-clinical animal model research
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Clinical indication: For “in-situ” vaccination (Neville et al, Cytokine, 2001, 16: 239) of patients with operable / inoperable bulky Colorectal cancer liver metastasis.
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PI: Dr. Ajay Maker, M.D., University of Illinois, Chicago.
2. Oncoquest™-PC:
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Description: Aggregon® with a recombinant human IL-2 and off-the-shelf common tumor antigen(s) found in Prostate cancer
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Stage: Research phase
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Clinical indication: Patients with early stage prostate cancer;
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PI: To be determined (TBD)
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